Add an option in Self-service settings and one in Email settings that allow the admin to configure a status that the call will change to once updated by a customer.
ie - service desk set status to 'waiting customer response', customer responds on portal (or email) and the call status automatically changes to set status so that the analyst can see that it has changed or been actioned
Another customer (ISDM UK) has just requested this functionality.
This is a great idea. Combined with the ability to take a call off suspend when a customer responds, it would make it much more efficient to respond to customers.